Perfusion

  • Perfusion
  • Perfusion

Mesenteric beds perfusion

Our perfusion system allows you to study the effect of vasoactive substances and electrical stimulation on the mesenteric beds of small animals.

Up to 4 mesenteric beds may be studied. Each organ lies on a stainless steel grid and bathes in a buffer solution.

The organ is perfused at a constant flow rate via its artery.

Several small cannulas are available to suit different artery sizes. Buffer flow rate is 5 to 10 times greater (maximum is 150ml/min.) than perfusion flow in order for perfusion to fully infuse bath liquid.

Pressure is measured just upstream of the cannula, reflecting changes in vascular tone.

Heated water is circulated continually through the space behind the bath walls to maintain the buffer solution at the right temperature.

Carbogen is released directly into the buffer solution.

In a standard system, one signal is acquired from each bed: perfusion pressure measured upstream of the mesenteric bed.

> See our perfusion system.

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